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Search SNIDD database |
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| NIMH/SNIDD Tracer Database Initiative | |||
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The National Institute of Mental Health (NIMH) and the Society for Non-Invasive Imaging in Drug
Development (SNIDD) are in the process of creating a centralized, searchable PET, SPECT, and MRI
tracer database as a resource for the scientific community. The goal of this effort is to promote
the use of imaging probes in preclinical and clinical research and in drug discovery to accelerate
the identification and validation of novel targets for therapeutic intervention in human diseases,
especially those with central nervous system components.
NIMH will maintain the tracer database as part of the Psychoactive Drug Screening Program (PDSP). The database will contain records for each radiotracer with relevant information such as target, research uses, pharmacology, pharmacokinetics, synthesis protocols, toxicology and safety data, dosimetry, other clinical data, IND info, permission to cross-reference pharmacology, toxicology, or safety data in a drug master file (if an IND exists), contact information, patent, etc. with appropriate safeguards in place to protect the intellectual property of proprietary compounds. | |||
Search SNIDD database | |||
| Disclaimer: | |||
| The toxicology and safety data in the NIMH/SNIDD database is provided as a service to the research community. It is being supplied to the database with no warranties, express or implied, including any warranty of merchantability or fitness for a particular purpose. It is the intention of NIMH/SNIDD that the originator/party submitting toxicology and safety data to the database not be liable for any claims or damages arising from a third party's use of the data; however, no indemnification is provided or intended. | |||
| * | Courtesy of Kung HF Specificity of diastereomers of [99mTc]TRODAT-1 as dopamine transporter imaging agents. Meegalla SK, Plossl K, Kung MP, Stevenson DA, Mu M, Kushner S, Liable-Sands LM, Rheingold AL, Kung HF. J Med Chem 1998 Feb 12;41(4):428-36 |